![Study protocol: phase 1 dose escalating study of Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) with oxaliplatin in peritoneal metastasis Study protocol: phase 1 dose escalating study of Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) with oxaliplatin in peritoneal metastasis](https://www.degruyter.com/document/doi/10.1515/pp-2018-0118/asset/graphic/j_pp-2018-0118_fig_001.jpg)
Study protocol: phase 1 dose escalating study of Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) with oxaliplatin in peritoneal metastasis
![DURVIT': a phase-I trial of single low-dose durvalumab (Medi4736) IntraTumourally injected in cervical cancer: safety, toxicity and effect on the primary tumour- and lymph node microenvironment | BMC Cancer | Full Text DURVIT': a phase-I trial of single low-dose durvalumab (Medi4736) IntraTumourally injected in cervical cancer: safety, toxicity and effect on the primary tumour- and lymph node microenvironment | BMC Cancer | Full Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-018-4764-0/MediaObjects/12885_2018_4764_Fig2_HTML.png)
DURVIT': a phase-I trial of single low-dose durvalumab (Medi4736) IntraTumourally injected in cervical cancer: safety, toxicity and effect on the primary tumour- and lymph node microenvironment | BMC Cancer | Full Text
![A hybrid design for dose‐finding oncology clinical trials - Liao - 2022 - International Journal of Cancer - Wiley Online Library A hybrid design for dose‐finding oncology clinical trials - Liao - 2022 - International Journal of Cancer - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/54bb178b-dd0f-4acd-92c3-212c06c4a96f/ijc34203-toc-0001-m.jpg)
A hybrid design for dose‐finding oncology clinical trials - Liao - 2022 - International Journal of Cancer - Wiley Online Library
![Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial | BMC Medical Research Methodology | Full Text Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial | BMC Medical Research Methodology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12874-022-01584-y/MediaObjects/12874_2022_1584_Fig1_HTML.png)
Adaptive design for identifying maximum tolerated dose early to accelerate dose-finding trial | BMC Medical Research Methodology | Full Text
A Multicenter Phase I/II Study of Obatoclax Mesylate Administered as a 3- or 24-Hour Infusion in Older Patients with Previously Untreated Acute Myeloid Leukemia | PLOS ONE
![Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial - eClinicalMedicine Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial - eClinicalMedicine](https://www.thelancet.com/cms/attachment/596fab91-d995-4289-b14d-237f412f9483/gr1_lrg.jpg)
Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial - eClinicalMedicine
![Study design for dose-escalation cohorts and DLT rate (as calculated by... | Download Scientific Diagram Study design for dose-escalation cohorts and DLT rate (as calculated by... | Download Scientific Diagram](https://www.researchgate.net/publication/259253363/figure/fig1/AS:601583003893781@1520439973618/Study-design-for-dose-escalation-cohorts-and-DLT-rate-as-calculated-by-smoothed-toxicity.png)
Study design for dose-escalation cohorts and DLT rate (as calculated by... | Download Scientific Diagram
![Autolack Dose spritzfertig für Ford DLT Gelb Basislack 1,0 Liter 1000ml : Amazon.de: Auto & Motorrad Autolack Dose spritzfertig für Ford DLT Gelb Basislack 1,0 Liter 1000ml : Amazon.de: Auto & Motorrad](https://m.media-amazon.com/images/I/71i9+LRcpBL._AC_UF1000,1000_QL80_.jpg)
Autolack Dose spritzfertig für Ford DLT Gelb Basislack 1,0 Liter 1000ml : Amazon.de: Auto & Motorrad
![Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study - ScienceDirect Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2451865416301053-gr3.jpg)
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study - ScienceDirect
Biostatistical intepretation series II Clinical Trials Phase I - mitigating misinterpretation risk in dose escalation studies
![Exposure driven dose escalation design with overdose control: Concept and first real life experience in an oncology phase I trial - ScienceDirect Exposure driven dose escalation design with overdose control: Concept and first real life experience in an oncology phase I trial - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2451865422000187-gr1.jpg)
Exposure driven dose escalation design with overdose control: Concept and first real life experience in an oncology phase I trial - ScienceDirect
![Principles of dose finding studies in cancer: a comparison of trial designs | Cancer Chemotherapy and Pharmacology Principles of dose finding studies in cancer: a comparison of trial designs | Cancer Chemotherapy and Pharmacology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00280-012-2059-8/MediaObjects/280_2012_2059_Fig2_HTML.gif)
Principles of dose finding studies in cancer: a comparison of trial designs | Cancer Chemotherapy and Pharmacology
![Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study. - Abstract - Europe PMC Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study. - Abstract - Europe PMC](https://europepmc.org/articles/PMC5898525/bin/gr2.jpg)
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study. - Abstract - Europe PMC
Three-plus-three dose escalation design. DLT, dose-limiting toxicity;... | Download Scientific Diagram
![Frontiers | A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy Frontiers | A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy](https://www.frontiersin.org/files/Articles/616264/fonc-11-616264-HTML/image_m/fonc-11-616264-g001.jpg)
Frontiers | A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy
![Bayesian Optimal Interval Design: A Simple and Well-Performing Design for Phase I Oncology Trials. - Abstract - Europe PMC Bayesian Optimal Interval Design: A Simple and Well-Performing Design for Phase I Oncology Trials. - Abstract - Europe PMC](https://europepmc.org/articles/PMC5047439/bin/nihms801570f1.jpg)
Bayesian Optimal Interval Design: A Simple and Well-Performing Design for Phase I Oncology Trials. - Abstract - Europe PMC
![Dose-finding clinical trial design for ordinal toxicity grades using the continuation ratio model: an extension of the continual reassessment method - Emily M Van Meter, Elizabeth Garrett-Mayer, Dipankar Bandyopadhyay, 2012 Dose-finding clinical trial design for ordinal toxicity grades using the continuation ratio model: an extension of the continual reassessment method - Emily M Van Meter, Elizabeth Garrett-Mayer, Dipankar Bandyopadhyay, 2012](https://journals.sagepub.com/cms/10.1177/1740774512443593/asset/images/large/10.1177_1740774512443593-fig1.jpeg)